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OBJECTIVE Compare the efficacy and safety of monotherapy with dulaglutide, a once-weekly GLP-1 receptor agonist, to metformin-treated patients with type 2 diabetes.Antidiabetic drugs (other than insulin). which increase insulin release such as sulfonylureas or which potentiate the effect of insulin such as metformin.. a Quick Overview. Bacteria release uremic toxins (cleared by the Kiney) …. • Links with Metformin. Shin et al. Gut 2013.

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